The second race stage of JoJo no Kimyou na Bouken: Steel Ball Run. 

In the 2nd STAGE, a desert crossing spanning roughly 750 miles- the land that Johnny Joestar and Gyro Zeppeli must challenge, is home to the area that is feared as the "Devil's Palm." In 1875, a threat lurking in said desert wiped out a cavalry of 26 people, eliciting fear from the local native people. As ominous incidents begin to unfold, they are forced to realize that this race is far more than a mere competition. The two press forward, where countless hidden motives collide. 

(Source: Warner Bros. Japan Anime, Netflix Anime, edited)

STEEL BALL RUN JoJo's Bizarre Adventure 2nd STAGE