The distant future. After reaching its peak, Earth's population fell into decline. AI was developed to help preserve the species and manage the ecosystem; a grand experiment in human diversity. Through genetic engineering, a diverse array of peoples, including beastfolk, magical beings, and more, was created to live in a diverse city separated into walled "clusters". 
 
Each cluster developed a unique culture, befitting of the people that lived there. Their lives, and the system, is continually maintained by the AI to ensure survival. 
 
(Source: Polygon Pictures) 
Note: The first four episodes were streamed in Japan on March 1st, the second four episodes were streamed in Japan on March 22nd, the third four episodes were streamed on April 12th. The episodes were streamed two weeks ahead of the Japanese broadcast on Crunchyroll beginning on March 23, 2022. The regular TV broadcast started on April 7, 2022.

Episode 1 - You Can't Run from Schoolwork

Episode 2 - You Can't Run from Memories

Episode 3 - You Can't Run from the Aquarium

Episode 4 - You Can't Run from Democracy

Episode 5 - You Can't Run from the Goddess

Episode 6 - You Can't Run from the Leader

Episode 7 - You Can't Run from Connections

Episode 8 - You Can't Run from Destiny

Episode 9 - You Can't Run from Domination

Episode 10 - You Can Run All You Want, But You Can't Get Away

Episode 11 - You Can't Run from Your True Feelings

Episode 12 - You Can't Run from the Extractors

Fuji TV

Crunchyroll

POLYGON PICTURES

Square Enix

GAGA

Dentsu

Rakuten

Slowcurve

BS Fuji

ESTAB LIFE: Great Escape